Generic Name: Domperidone Maleate 5mg
Company Name: Incepta Pharmaceuticals Ltd
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Indications of Omidon 60ml
Omidon 60ml is a prescription medication that is used to treat indigestion, nausea, and vomiting. It inhibits the substance in the brain that causes nausea or vomiting, as well as increases the movement of food in the stomach, which improves digestion. Omidon 60ml is taken before meals in the prescribed dose and duration.
Pharmacology
Domperidone is a dopamine antagonist that primarily blocks dopamine receptors in the chemoreceptor trigger Zone (CTZ) and stomach. Its gastroprokinetic activity is based on its ability to block dopamine receptors, which influence gastrointestinal motility. Omidon 60ml has almost no effect on the dopaminergic receptors within the brain due to its weak passage through the blood-brain barrier, barring psychotropic and neurologic side effects. Domperidone restores normal upper gastrointestinal motility and tone, promotes gastric purging, improves antral and duodenal peristalsis, and regulates pylorus compression. Domperidone also increases esophageal peristalsis and decreases esophageal sphincter weight, preventing the release of gastric contents.
Dosage & Administration of Omidon 60ml
Omidon 60ml tablet should be taken 15-30 minutes before meals and, if necessary, before retiring.
The usual recommended oral dose of Domperidone is as follows:
In acute and subacute conditions (especially acute nausea and vomiting):
By rectum in suppositories:
Interaction of Omidon 10
Domperidone may reduce the hypoprolactemic effect of bromocriptine. Domperidone's effect on Gl function may be mitigated by antimuscarinics and opioid analgesics. Domperidone should be used with caution when combined with MAO (monoamine oxidase) inhibitors.
Contraindications
Domperidone may reduce the hypo prolactin effect of bromocriptine. Domperidone's effect on Gl function may be mitigated by antimuscarinics and opioid analgesics. Domperidone should be used with caution when combined with MAO (monoamine oxidase) inhibitors.
Side Effects
Hyperprolactinemia is a side effect of domperidone (1.3 percent ). Galactorrhea, breast growth, discomfort, and a decrease in libido are all possible side effects. During domperidone treatment, dry mouth (1 percent), thirst, headache (1.2 percent), nervousness, drowsiness (0.4 percent), diarrhea (0.2 percent), skin rash, and itching (0.1 percent) are all possible side effects. Clinical investigations show that extrapyramidal responses occur in 0.05 percent of patients.
Pregnancy & Lactation
The security of domperidone has not been demonstrated and it is subsequently not prescribed during pregnancy. Creature considers have not illustrated the teratogenic impact on the baby. Omidon 60ml may accelerate galactorrhea and progress post-natal lactation. It is emitted in breast drain but in exceptionally little amounts inadequately to be considered hurtful.
Precautions & Warnings
Omidon 60ml ought to be utilized with supreme caution within the case of children since there may be an expanded chance of extrapyramidal responses in youthful children since of a not entirely created blood-brain boundary. Since domperidone is profoundly metabolized in the liver, it ought to be utilized with caution in persistent hepatic disability.
Storage Conditions
Do not store at temperatures above 30°C. Keep out of the reach of youngsters and away from light.
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